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Séminaire du CMLA : Modeling protein-protein interactions at large scale

le 22 novembre 2018
13h00 - 14h00

Séminaire animé par Élodie Lainé, Sorbonne Université.



Protein interactions are essential to all biological processes. Many proteins interact with different partners, some of them binding to different regions at its surface, others using the same region. Our knowledge of protein interaction networks and of protein surface usage is largely incomplete.

I will present several methodological efforts conducted in our team to determine who interacts with whom in the cell and how. We describe protein surfaces using a small number of biologically meaningful properties to predict DNA- and protein-binding sites and estimate the number of partners a protein may have.

We cross these predictions with complete cross-docking calculations to discriminate protein partners from non-interactors at large scale.
Type :
Séminaires - conférences
Lieu(x) :
Campus de Cachan
Bâtiment Cournot, salle C103


Un buffet est prévu avant l'exposé, vers 12h30.

Merci de vous inscrire, ainsi que vos invitées et invités avant le mardi 20 novembre à 11h à l'adresse suivante.

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